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Old 11-27-2008, 02:46 PM
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Default Re: ALERT: Orijen dry cat users.

Pakcu tak yah risau sangat. Kes nih berlaku unik di Australia disebabkan radiasi.
Ni email dari Champion Petfood, Canada untuk distributors Orijen.
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Dear ORIJEN distributors,
Please see the attached and updated file on the situation concerning ORIJEN Cat Food in Australia. As test results continue to roll in they continue to strongly support our position of irradiation as the principal cause. Please read through the attached “Questions and Answers” document carefully and write or call with any questions.
I strongly suggest you provide this data to all of your sales staff as well as to your key retail accounts. Here in Canada we have already met with all of our distributors and have either spoken to their sales staff directly or by conference call. We have taken further action by contacting all our key retail accounts here in Canada to advise them of the situation and to assure them markets outside of Australia are not affected. This “proactive” strategy appears to be working well and we have so far been met with a great deal of positive reactions as retailers appreciate us notifying them before they learn about the situation from a customer or competitor.
Although we are removing our foods from Australia the research remains ongoing as we feel it is important to contribute to the growing body of knowledge connecting the irradiation of nutrient dense foods and the health of cats.


Peter A. Muhlenfeld
Champion Petfoods Ltd.
T 780.939.6888

<<Attachment>>

PG 1
ORIJEN CAT FOOD AUSTRALIA
On November 20th, 2008 Champion Petfoods announced a
VOLUNTARY RECALL of ORIJEN brand cat food sold in Australia.
The recall is restricted to
AUSTRALIA ONLY and was issued in response to reports from the Australian veterinary community of 27
cats showing neurological symptoms after consuming ORIJEN.
While there is no definitive link between ORIJEN CAT food and illness in the Australian cats, we have recalled our product from
Australia as a precautionary measure.
The following ‘Questions and Answers’ are intended to explain:

WHY THE PROBLEM IS EXCLUSIVE TO AUSTRALIA
THE ROOT CAUSE OF THE PROBLEM
PREVENTATIVE MEASURES AND AVAILABLE TREATMENT OPTIONS
QUESTIONS AND ANSWERS
Q:
DOES THE RECALL EXTEND BEYOND AUSTRALIA?

A: No, The recall is for
AUSTRALIA ONLY

Q:
HOW DO YOU KNOW THE PROBLEM IS LIMITED TO AUSTRALIA?

A:
WHILE ORIJEN SALES IN AUSTRALIA ACCOUNT FOR LESS THAN ¼ OF 1 PERCENT OF TOTAL SALES, AUSTRALIA
ACCOUNTS FOR 100% OF CASES.

ORIJEN was sold in Australia only for a 9 month period of February through October 2008.
During this time ONLY 6 PALLETS of ORIJEN CAT food actually entered retail distribution in Australia. This equates to
200 Australian cats fed daily over the 9 month period.
Of these 200 cats, 27 are reported having the syndrome of which 4 have been unfortunately euthanized and 4 that are
thankfully recovering.
During the same nine month period, shipments of ORIJEN CAT food equivalent to feed 85,000 cats were made to 49
other countries.
ZERO
cases were reported outside of Australia.
Q:
WHAT IS DIFFERENT ABOUT AUSTRALIA?

A:
IRRADIATION

Champion Petfoods has investigated factors that make Australia unique from our other ORIJEN markets, both export and domestic.
Of the 50 countries to which we supply ORIJEN, Australia is the only country that requires the IRRADIATION TREATMENT
of ORIJEN cat foods.
UPDATED, NOVEMBER 26, 2008
PG 2
Q:
WHAT IS IRRADIATION?

A: Irradiation is a process that passes Cobalt 60 gamma rays through food to reduce microbial hazards, specifically, in this case -
imported pet foods containing fresh meats.
Q:
IS ALL DRY CAT FOOD IN AUSTRALIA IRRADIATED?

A:
NO.

The overwhelming majority of dry cat foods in Australia do not require irradiation. ORIJEN is one of very few that must
comply with this regulation.
Q:
WHY IS ORIJEN IRRADIATED?

A: Australia requires irradiation on foods that include fresh meats or that have been cooked at low temperatures.
Other pet foods that are cooked at high temperatures or are made with chicken meal, turkey meal, fish meal or other
ingredients that are pre-cooked at high temperatures prior to inclusion in pet foods do not have to be irradiated.
Q:
ISN’T IRRADIATION GENERALLY RECOGNIZED AS SAFE?

A:
YES. But Irradiation is typically applied to human foods at doses between 5-10kGY.
ORIJEN in Australia received a minimum level of 50 kGY and records recovered from the Australian irradiation facility
show that ORIJEN was irradiated to levels reaching 61 kGY.
THESE ARE VERY SUBSTANTIAL LEVELS OF IRRADIATION.

Studies indicate that cats fed dry cat food irradiated at levels between 36 and 47kGY develop the same neurological
symptoms as seen in the Australian cats.
Q:
HOW DOES IRRADIATION AFFECT ORIJEN?

A: In recent weeks, Champion Petfoods has conducted extensive testing on ORIJEN Cat sold in Australia. From a combination of
laboratory test results, scientific papers from reputable journals, and consultation from various nutritional experts and veterinarians
around the world, we have discovered 2 primary factors:
1) VITAMIN A DEPLETION IN IRRADIATED FOODS
Our tests show that irradiation of ORIJEN Cat at 50kGY causes a depletion of vitamin A of up to 77%. The irradiation
levels applied to ORIJEN in Australia exceeded this amount.
We tested ORIJEN cat foods at varying levels of irradiation (0 kGY (control), 25kGY and 50kGY). The results show a
direct and linear relationship between the increase in irradiation dosage and vitamin A depletion. In other words, more
vitamins were depleted as the level of irradiation increased.
Literature published by the American College of Veterinary Pathologists (2007) shows that depletion of vitamin A from
irradiated cat food is associated with the same symptoms in cats as are reported in Australia (CASSIDY ET. AL, 2007).
An excerpt from the American College of Veterinary Pathologists’ study supports this finding:
“Both SPF (specific pathogen free) and conventional status cats had been fed to appetite on the same commercial formula ration
(Gilbertson and Page Ltd., Welwyn Garden City, UK),
except that the ration fed to the SPF cats had been irradiated by a
single-exposure gamma-radiation treatment between 36.3 and 47.3 kGy (Cobalt 60 irradiator; Isotron Ireland, Tullamore,
Ireland).
The irradiated diet was consumed to the same extent as the non-irradiated diet, and affected animals did not lose weight
until the developing ataxia hindered their access to food…
Following supplementation of the irradiated diet with pasteurized
proprietary tinned cat food in the winter of 2001 and, ultimately, the replacement of the irradiated diet with an equivalent
pasteurized diet, no further cases occurred”.

continues on pg. 3
PG 3
The report describes an investigation of 8 cases where the disease is associated with the long-term feeding of cats on a
gamma-irradiated dry food diet. This study is available on the internet from the link below:
2) THE FORMATION AND RELEASE OF FREE RADICALS IN IRRADIATED FOODS
A second major impact of irradiation is the formation and release of free radicals.
Irradiation does not affect all foods equally. ORIJEN is a nutritionally dense food with much higher levels of long-chain
fatty acids (DHA, EPA) than conventional pet foods. These fatty acids are susceptible to oxidation following irradiation.
Bi-products from fatty acid oxidation, mainly free radicals, are released into the body with the potential to cause tissue
damage.
Combined with the loss of antioxidant vitamins (see Vitamin A described above), free radicals are thought to be a major
contributing factor.
When irradiation is applied to food, the molecular structure of long chain fatty acids (DHA, EPA) is altered. This causes
the formation of free radicals that are then released into the body.
ORIJEN CAT foods contain very high levels of EPA and DHA unsaturated fatty acids and therefore have a much greater
potential for free radical formation (in response to irradiation) than do conventional dry cat foods.
Scientific evidence shows that increased oxidative bi-products combined with decreased presence of antioxidant
vitamins (see above) are consistent with the symptoms shown in Australian cats. The fact that cats in Australia treated
with vitamin and antioxidant supplementation have shown improvements supports this finding.
An excerpt from the American College of Veterinary Pathologists’ study supports this position:
“Irradiation is known to reduce the vitamin content of food, the effect of which may be indirect, in that inadequate amounts of these
compounds may be available to counteract the effects of free radicals generated by normal cell metabolism. A previous study found
that irradiation of a feline diet containing 9.8% fat with a 2- to 5-Mrad dose totally destroyed its vitamin A and
β-carotene content,
whereas thiamine, vitamin B6 (pyridoxine), and folic acid were depleted to a lesser extent, and vitamin E concentrations appeared
to be unaffected by this dose of radiation.
The relatively high dietary fat requirement of cats may be significant in this context
in that irradiation of this fat component could potentially generate higher concentrations of micronutrient-damaging free
radicals than would be generated on irradiating diets of lower fat content.”

Q:
WHAT SHOULD I DO IF I LIVE IN AUSTRALIA AND FEED ORIJEN CAT?

A: Please return any unused portion of ORIJEN Cat food to the place of purchase for a full refund. If you think that you see any
symptoms of this syndrome in your cat please contact your veterinary immediately. There is evidence that health can improve with
vitamin and antioxidant supplementation.
SIGNS
Changes in your cat’s way of walking – the gait may be wobbly, or your cat’s legs may slip under when going around
a corner
Unwilling to jump onto sofa or bed
Loss of balance and falling off of bench-tops, tables etc
PREVENTATIVE MEASURES
Fresh food carnivorous diet consisting of fresh meat, occasional fish, occasional vegetables
Premium dry food if unable to feed the above
continues from pg. 2
continues on pg. 4
Anti-oxidants – Cysteine/Glutathione to protect liver and kidneys – for 6-8 weeks
Omega fatty acids ie. Fish Oil to act as anti-inflammatory and anti-oxidant
Vitamin A – oral form for 3 week period – weight of the animal and specific dose is important, please consult with your
vet or with Champion Petfoods for specific dosages.
Regular exercise and play
Access to fresh spring water or reverse osmosis (RO) water
TREATMENT OPTIONS
Anti-oxidants, Omega fatty acid, Vitamins
Prednisone, Metacam or Antibiotics if needed on veterinarian’s advice
Exercise, movement and physical therapy are crucial for recovery
Q:
ARE ORIJEN DOG FOODS IN AUSTRALIA ALSO IRRADIATED?

A:
YES. All ORIJEN diets sold in Australia and subjected to the same irradiation process.
Q:
ARE ORIJEN DOG FOODS SAFE?

A: Champion Petfoods has examined the issue of safety in dogs very closely.
ORIJEN dog diets have been sold and consumed in Australia over the same 9 months that ORIJEN Cat has been sold,
only in much greater quantities.
NO DOGS HAVE BEEN AFFECTED.
Dogs and cats are two different species with different nutritional needs and
metabolic pathways. For example, cats require higher levels of vitamins than dogs (AAFCO 2008), and cats are highly
sensitive to changes in vitamins or oxidative by-products (such as occur from irradiation).
There are no reports or scientific studies linking irradiation to health problems in dogs.
Q:
WILL CHAMPION CONTINUE TO SELL ORIJEN PRODUCTS IN AUSTRALIA?

A:
NO.

Veterinarians in Australia have recently reported households where both dogs and cats are present and cases where cats prefer
ORIJEN dog food over the brand of cat food they receive.
Of the 27 cases of illness, at least 2 cases involve cats eating ORIJEN dog food.
As we are unable to control for cats consuming ORIJEN dog food, there is a small but measurable risk of cross-feeding
in dual pet (dogs and cats) households.
Implemented as a precautionary measure to prevent cross contamination, Champion Petfoods has elected to stop
selling ORIJEN dog foods in Australia.
EVERY ORIJEN PRODUCT IS RIGOROUSLY TESTED BEFORE LEAVING OUR FACTORY. WITH THE EXCEPTION OF ORIJEN CAT
FOODS IN AUSTRALIA ALL ORIJEN PRODUCTS SHOULD BE USED IN CONFIDENCE.
PG 4
continues from pg. 3
Champion Petfoods Ltd. is a family-owned award-winning pet food producer. For over 25 years, our mission
is to promote the health of dogs and cats worldwide – a mandate in which we are passionately engaged.
Every member of our family and the vast majority of our staff share their homes with beloved dogs and cats. These relationships
enrich our lives and empower our spirits. At Champion, making pet food is much more than a business operation - it is our
calling, our true passion.
It is with our own pets in mind that we extend our deepest empathy to the Australian families affected by this regrettable
circumstance. While we will no longer sell any of our pet foods in Australia we remain committed to on-going research into this
case with the hope that our findings can be used to better inform the international community on the potential effects of
irradiation on nutrient dense dry cat food.
Sincerely,
References
1. Cassidy JP, Caulfield C, Jones BR, Worrall S, Conlon L, Palmer AC, Kelly J. Leukoencephalomyelopathy in Specific Pathogen-free Cats. Vet
Pathology. 44: 912-916. 2007
2. Lushchak VI. Free Radical Oxidation of Proteins and Its Relationship with Functional State of Organisms. Biochemistry (Moscow), Vol. 72, No. 8:
809-827. 2007
3. Lee KH, Yook HS, Lee JW, Park WJ, Kim KS, Byun MW. Quenching Mechanism and Kinetics of Ascorbyl Palmitate for the Reduction of the Gamma
Irradiation-Induced Oxidation of Oils. JAOCS, Vol. 76, No.8:921-925. 1999.
4. Mahrour A, Caillet S, Nketsia-Tabiri J, Lacroix M. The Antioxidant Effect of Natural Substances on Lipids During Irradiation of Chicken Legs.
JAOCS, Vol. 80, no. 7: 679-684. 2003.
5. Fujioka K, Shibamoto T. Formation of Genotoxic Dicarbonyl Compounds in Dietary Oils upon Oxidation. Lipids, Vol. 39, no. 5: 481-486. 2004.
6. Leeson S, Marcotte M. Irradiation of poultry feed II. Effect on nutrient composition. World’s Poultry Science Journal, 49: 120-131. 1993.
7. Health Canada Government Website. Alteration of Chemical, Physical and Microbiological Characteristics. Section (d): i. Odour. Updated: 2003.
9503-90 Avenue,
Morinville, Alberta
CANADA
T8R 1K7
phone. 780 939.6888
email. customerservice@championpetfoods.com
www.championpetfoods.com
PG 5
Reinhard Muhlenfeld
President & Founder
Champion Petfoods Ltd.
Peter Muhlenfeld
Sales and Marketing
Manager
Champion Petfoods Ltd.
Henry Van de Vliert
Production Manager
Champion Petfoods Ltd.
Jeff Johnston
Procurement and
Nutrition Coordinator
Champion Petfoods Ltd.
Gordon Demaniuk
Quality Assurance
Manager
Champion Petfoods Ltd.
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